CpcT family
Description
Characterized in Synechococcus sp. PCC 7002 and Nostoc sp. PCC7120 to attach a PCB at Cys-153 of beta-PC (Shen et al., 2006; Zhao et al., 2007a,b). Nostoc sp. PCC 7120 CpcT also attaches PCB to Cys 155 of PecB (i.e. beta-PEC; Zhao et al., 2007a,b). Crystal structures of CpcT from Nostoc sp. PCC7120 and its complex with phycocyanobilin, have been obtained at 1.95 and 2.50 Å resolution, respectively (Zhou et al. 2014). CpcT forms a dimer and adopts a calyx-shaped beta-barrel fold.
Motif
A motif characterising this family is available.
References
- Shen et al., 2006. Identification and characterization of a new class of bilin lyase: the cpcT gene encodes a bilin lyase responsible for attachment of phycocyanobilin to Cys-153 on the beta subunit of phycocyanin in Synechococcus sp. PCC 7002 J Biol Chem, 281, 17768-17778.
- Zhao et al., 2007b. Lyase activities of CpcS- and CpcT-like proteins from Nostoc PCC7120 and sequential reconstitution of binding sites of phycoerythrocyanin and phycocyanin beta-subunits J Biol Chem, 282, 34093-34103.
- Zhou et al., 2014. Structure and mechanism of the phycobilin lyase CpcT J Biol Chem, 289, 26677-26689.
Showing only unsure genes
| Gene | Locus tag | Genbank | Species | Strain | PBP in rods | Pigment type | Remark | Length | Last change |
|---|---|---|---|---|---|---|---|---|---|
| CpcT family | GTHECHR1104 | XP_001713602.1 | Guillardia theta | CCMP2712 | Cr-PE 545 | n.a. | Low protoscan score but best BLASTP match to the CpcT family. This cpcT-like gene was characterized by complementation of Synechocystis sp. PCC6803 cpcT (Bolte et al. 2008). However, since G. theta possesses PE (Cr-PE 545) not PC, the function of this gene (despite its closest similarity to cpcT than cpeT families) must likely be to attach a PEB at Cys-159 of beta-PE. | 222 | 09-28-2012 |
| CpcT family | CMK263C | Cyanidioschyzon merolae | 10D | PC | 1 | found by tblastn | 263 | 02-21-2012 | |
| CpcT family | HAN_1g134 | XP_001712298.1 | Hemiselmis andersenii | CCMP644 | Cr-PE 555 | n.a. | 221 | 01-24-2012 | |
| CpcT family | Pse7367_2699 | YP_007103382.1 | Pseudanabaena sp. | PCC7367 | PC+PEI | Low protomatch score | 202 | 06-20-2013 |
Model strains, Marine strains
Last update: 18 Jan 2018 16:51:37
